The Entertainer in Telford Shopping Centre will move from its current unit near Primark and Marks & Spencer into a new shop on the former BHS site.
The children's store has been in its current place since it opened in the town, but will reopen near the Northern Quarter on October 6.
BHS in Telford closed in August 2016, one of 164 shut down across the country.
Bargain hunters gathered outside the department store ahead of its last 9am opening, hoping to find cut-price clothing, food and DVDs.
The closure came after the company failed to find a buyer.